Products for Research Use Only

MRPS18A polyclonal antibody

CAT: 0384-BS65165-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65165-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mitochondrial ribosomal protein S18A (MRPS18A) Homo sapiens Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondria
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Product Name Alternative
MRPS18A; 28S ribosomal protein S18a; mitochondrial; MRP-S18-a; Mrps18a; S18mt-a; 28S ribosomal protein S18-3, mitochondrial; MRP-S18-3
Swiss Prot
Q9NVS2
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MRPS18A. AA range:81-130
Conjugation
Unconjugated
Applications
IHC-p, IF (paraffin section), ELISA
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Modification
Unmodification
Molecular Weight
/
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MRP-S18A Polyclonal Antibody detects endogenous levels of MRP-S18A protein.
Applications Notes
Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using MRPS18A Antibody. The picture on the right is blocked with the synthesized peptide.
Host or Source
Rabbit