Products for Research Use Only

GUF1 polyclonal antibody

CAT: 0384-BS65163-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65163-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GUF1 homolog, GTPase (GUF1) Homo sapiens This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Product Name Alternative
GUF1; Translation factor GUF1; mitochondrial; Elongation factor 4 homolog; EF-4; GTPase GUF1; Ribosomal back-translocase
Swiss Prot
Q8N442
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470
Conjugation
Unconjugated
Applications
IHC-p, IF (paraffin section), ELISA
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Modification
Unmodification
Molecular Weight
/
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GUF1 Polyclonal Antibody detects endogenous levels of GUF1 protein.
Applications Notes
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using GUF1 Antibody. The picture on the right is blocked with the synthesized peptide.
Host or Source
Rabbit