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Cullin 3 polyclonal antibody

CAT: 0384-BS65137-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65137-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cullin 3 (CUL3) Homo sapiens This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Product Name Alternative
CUL3; KIAA0617; Cullin-3; CUL-3
Swiss Prot
Q13618
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Cullin 3. AA range:1-50
Conjugation
Unconjugated
Applications
WB, IHC-p, IF (paraffin section), ELISA
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Modification
Unmodification
Molecular Weight
~ 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CUL-3 Polyclonal Antibody detects endogenous levels of CUL-3 protein.
Applications Notes
Western Blot analysis of various cells using CUL-3 Polyclonal Antibody diluted at 1: 1000
Host or Source
Rabbit

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