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DAB2 Polyclonal Antibody

CAT: 0384-BS65935-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65935-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
DAB 2; DAB2; DAB2_HUMAN; Differentially expressed protein 2; Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein) ; disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) ; Disabled homolog 2; Disabled homolog 2 mitogen responsive phosphoprotein (Drosophila) ; Disabled homolog 2 mitogen responsive phosphoprotein; disabled homolog 2 mitogen-responsive phosphoprotein (Drosophila) ; DOC 2; DOC2; FLJ26626; Mitogen responsive phosphoprotein.
Swiss Prot
P98082
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig
Immunogen
KLH conjugated synthetic peptide derived from human DAB2:31-130/770
Conjugation
Unconjugated
Applications
FCM
Dilution
Flow-Cyt=1ug/Test
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
82kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
DAB2 Polyclonal Antibody detects endogenous levels of DAB2 protein.
Host or Source
Rabbit

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