KAT2B Polyclonal Antibody

• Background:

  Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.

• Structure Composition:

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative:

  GCN5; PCAF; CAF; CREBBP associated factor; GCN5; GCN5L; GCN5L1 antibody Histone acetylase PCAF; Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; K (lysine) acetyltransferase 2B; KAT2B; KAT2B_HUMAN; Lysine acetyltransferase 2B; P antibody P/CAF; p300/CBP associated factor; P300/CBP-associated factor; Pcaf.

• Swiss Prot:

  Q92831

• Reactivity:

  Human, Mouse, Rat, Chicken, Dog, Pig, Horse

• Immunogen:

  KLH conjugated synthetic peptide derived from human KAT2B:451-550/832

• Conjugation:

  Unconjugated

• Related Pathways:

  Nuclear Receptor Signaling, Epigenetic Writers and Erasers of Histone H3, Epigenetic Writers and Erasers of Histones H2A H2B and H4

• Applications:

  FCM

• Dilution:

  Flow-Cyt=1ug/Test

• Purity:

  Affinity purified by Protein A

• Modification:

  Unmodification

• Molecular Weight:

  92kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  KAT2B Polyclonal Antibody detects endogenous levels of KAT2B protein.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4