SEC62 Polyclonal Antibody

• Background :

  The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]

• Structure Composition :

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative :

  Dtrp1; FLJ32803; hTP-1; HTP1; Membrane protein SEC62, S.cerevisiae, homolog of; OTTHUMP00000213390; sec62; SEC62 homolog (S. cerevisiae) ; SEC62_HUMAN; TLOC1; TP-1; Translocation protein 1; Translocation protein sec62.

• Swiss Prot :

  Q99442

• Reactivity :

  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep

• Immunogen :

  KLH conjugated synthetic peptide derived from human SEC62:251-350/399

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB=1:500-2000

• Purity :

  Affinity purified by Protein A

• Modification :

  Unmodification

• Molecular Weight :

  ~48kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -22°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  SEC62 Polyclonal Antibody detects endogenous levels of SEC62 protein.

• Applications Notes :

  Primary: Anti- SEC62 at 1/1000 dilution

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4