SLC10A1Polyclonal Antibody

• Background :

  Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization (SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1) .[supplied by OMIM]

• Structure Composition :

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative :

  Na+/taurocholate Cotransporting Polypeptide; Na (+) /bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na / bile acid cotransporter; Na / taurocholate transport protein; Na (+) /taurocholate transport protein; NTCP; NTCP1; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; Slc10a1 protein; Slc10a1; SBACT; SLC10A1; NTCP_HUMAN.

• Swiss Prot :

  Q14973

• Reactivity :

  Human, Mouse, Rat, Dog, Horse, Rabbit

• Immunogen :

  KLH conjugated synthetic peptide derived from human NTCP:21-120/349

• Conjugation :

  Unconjugated

• Applications :

  ICC

• Dilution :

  ICC=1:100-500

• Purity :

  Affinity purified by Protein A

• Modification :

  Unmodification

• Molecular Weight :

  ~38kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -21°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  SLC10A1 Polyclonal Antibody detects endogenous levels of SLC10A1 protein.

• Applications Notes :

  Tissue/cell: Siha cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (SLC10A1) Polyclonal Antibody, Unconjugated 1:200, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (5ug/ml, blue, C-0033) was used to stain the cell nuclei.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4