AP2 alpha + beta Polyclonal Antibody

• Background :

  The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth and development. The factors have also been implicated in the control of cell proliferation, viral transformation, and oncogenesis. AP2 seems to play in important role in human breast cancer. AP2 alpha is the only AP2 protein required for early morphogenesis of the lens vesicle. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.

• Structure Composition :

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative :

  Activating enhancer binding protein 2 alpha; Activating enhancer binding protein 2 beta; AP2TF; TFAP2; TFAP2A; TFAP2B; Transcription factor AP2 alpha; Transcription factor AP2 beta; AP2A_HUMAN; AP2B_HUMAN.

• Swiss Prot :

  P05549

• Reactivity :

  Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep

• Immunogen :

  KLH conjugated synthetic peptide derived from human AP2 alpha + beta:201-300/437

• Conjugation :

  Unconjugated

• Related Pathways :

  Vesicle Trafficking presynaptic signaling

• Applications :

  FCM

• Dilution :

  Flow-Cyt=1ug/test

• Purity :

  Affinity purified by Protein A

• Modification :

  Unmodification

• Molecular Weight :

  48kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  AP2 alpha + beta Polyclonal Antibody detects endogenous levels of AP2 alpha + beta protein.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4