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Hemogen Polyclonal Antibody

CAT: 0384-BS65720-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65720-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Hemogen is a 484 amino acid protein encoded by the human gene HEMGN. Hemogen is a nuclear protein that is expressed in hematopoietic precursor cells and can be detected in CD34+ and K-562 leukemia cell line. It is also expressed in bone marrow, testis, thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. Hemogen is down-regulated during megakaryocytic differentiation of K-562 cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) (at protein level) . It can be up-regulated in normal PBMCs by mitogens.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
EDAG; EDAG-1; Erythroid differentiation-associated gene protein; HEMGN; HEMGN_HUMAN; Hemogen; Hemopoietic gene protein; Negative differentiation regulator protein.
Swiss Prot
Q9BXL5
Reactivity
Human
Immunogen
KLH conjugated synthetic peptide derived from human Hemogen/EDAG:51-150/484
Conjugation
Unconjugated
Applications
FCM
Dilution
Flow-Cyt=1ug/test
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
55kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Hemogen Polyclonal Antibody detects endogenous levels of Hemogen protein.
Host or Source
Rabbit

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