CD55 Polyclonal Antibody

• Background:

  This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF) ; binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) . Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined.

• Structure Composition:

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative:

  CD 55; CD55 antigen; CD55 Cromer blood group system; CD55 molecule; CD55 molecule, decay accelerating factor for complement (Cromer blood group) ; Cd55a; Complement decay accelerating factor; Complement decay-accelerating factor; Complement decay-accelerating factor, GPI-anchored; CR; CROM; Cromer Blood Group antigen; Cromer blood group system; DAF; Daf-GPI; DAF_HUMAN; Daf1; Dcay accelerating factor for complement (CD55, Cromer blood group system) ; Decay accelarating factor 1, isoform CRA_a; Decay accelerating factor (GPI-form) ; Decay Accelerating Factor for Complement; Decay accelerating factor GPI-form; Decay accelerating factor soluble-form; GPI-DAF; TC.

• Swiss Prot:

  Q61476

• Reactivity:

  Mouse, Rat

• Immunogen:

  KLH conjugated synthetic peptide derived from mouse CD55

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB=1:500-2000

• Purity:

  Affinity purified by Protein A

• Modification:

  Unmodification

• Molecular Weight:

  70-75 kD

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CD55 Polyclonal Antibody detects endogenous levels of CD55 protein.

• Applications Notes:

  Sample: Lane 1: Hela (Human) Cell Lysate at 30 ug Lane 2: Huvec (Human) Cell Lysate at 30 ug Lane 3: A549 (Human) Cell Lysate at 30 ug Primary: Anti-CD55 at 1/1000 dilution

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4