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TBCEL Polyclonal Antibody

CAT: 0384-BS65645-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65645-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TBCEL is a 424 amino acid cytoplasmic protein that acts as a regulator of tubulin stability. While abundantly expressed in testis, TBCEL is also present in several tissues at a much lower level. TBCEL contains seven LRR (leucine-rich) repeats, one LRRCT domain and one ubiquitin-like domain. The gene that encodes TBCEL consists of 66,704 bases and maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
EL; Leucine-rich repeat-containing protein 35; LRRC35; TBCEL; TBCEL_HUMAN; Tubulin folding cofactor E-like; Tubulin-specific chaperone cofactor E-like protein.
Swiss Prot
Q5QJ74
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated synthetic peptide derived from human TBCEL
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
48 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TBCEL Polyclonal Antibody detects endogenous levels of TBCEL protein.
Applications Notes
Sample: Lane 1: U-2OS (Human) Cell Lysate at 30 ug Lane 2: HUVEC (Human) Cell Lysate at 30 ug Lane 3: SH-SY5Y (Human) Cell Lysate at 30 ug Lane 4: HL-60 (Human) Cell Lysate at 30 ug Lane 5: Cerebrum (Mouse) Lysate at 40 ug Lane 6: Cerebrum (Rat) Lysate at 40 ug Lane 7: Kidney (Mouse) Lysate at 40 ug Lane 8: Testis (Mouse) Lysate at 40 ug Lane 9: Testis (Rat) Lysate at 40 ug Lane 10: Stomach (Rat) Lysate at 40 ug Primary: Anti-TBCEL at 1/1000 dilution
Host or Source
Rabbit

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