ADM2 Polyclonal Antibody

• Background:

  This gene encodes a protein which is a member of the calcitonin-related hormones. The encoded protein is involved in maintaining homeostasis in many tissues, acting via CRLR/RAMP receptor (calcitonin receptor-like receptor/receptor activity-modifying protein) complexes. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]. TISSUE SPECIFICITY:High expression detected in the submaxillary gland, kidney, stomach, and mesentery, followed by the pituitary, lung, pancreas, intestines, spleen, thymus and ovary. Expressed mainly in the intermediate lobe of the pituitary, with sporadic in the anterior lobe.

• Structure Composition:

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative:

  ADM2; IMD; Intermedin; Adrenomedullin-2; AM2; IMDL; IMDS; ADM2_HUMAN; Adrenomedullin 2; dJ579N16.4; FLJ21135; IMDL; Intermedin-long; Intermedin-short.

• Swiss Prot:

  Q7Z4H4

• Reactivity:

  Human, Mouse, Rat, Pig, Horse, Rabbit

• Immunogen:

  KLH conjugated synthetic peptide derived from human Intermedin:75-148/148

• Conjugation:

  Unconjugated

• Applications:

  IHC-P

• Dilution:

  IHC-P=1:100-500

• Purity:

  Affinity purified by Protein A

• Modification:

  Unmodification

• Molecular Weight:

  5.2kD

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  ADM2 Polyclonal Antibody detects endogenous levels of ADM2 protein.

• Applications Notes:

  Paraformaldehyde-fixed, paraffin embedded (Rat brain) ; Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (ADM2) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4