FRMPD2 Polyclonal Antibody

• Background :

  This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants.

• Structure Composition :

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative :

  FERM and PDZ domain containing protein 2; PDZ domain containing protein 4; PDZ domain containing protein 5C; PDZ domain containing 4 PDZD5C; PDZK4; PDZK5C; FRPD2_HUMAN.

• Swiss Prot :

  Q68DX3

• Reactivity :

  Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep

• Immunogen :

  KLH conjugated synthetic peptide derived from human PDZK4:1001-1100/1309

• Conjugation :

  Unconjugated

• Applications :

  IHC-P

• Dilution :

  IHC-P=1:100-500

• Purity :

  Affinity purified by Protein A

• Modification :

  Unmodification

• Molecular Weight :

  144kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  FRMPD2 Polyclonal Antibody detects endogenous levels of FRMPD2 protein.

• Applications Notes :

  Paraformaldehyde-fixed, paraffin embedded (mouse brain) ; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FRMPD2) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4