LRRC41 Polyclonal Antibody

CAT: 0384-BS65424-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS65424-01Size:50 µL
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Background
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
Elongin BC interacting leucine rich repeat protein; Leucine rich repeat containing 41; Leucine rich repeat containing protein 41; MUF1; PP7759; LRC41_HUMAN.
Swiss Prot
Q15345
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep
Immunogen
KLH conjugated synthetic peptide derived from human LRRC41:331-430/812
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
79 kD
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LRRC41 Polyclonal Antibody detects endogenous levels of LRRC41 protein.
Applications Notes
Primary: Anti-LRRC41 at 1/1000 dilution
Host or Source
Rabbit

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