RECK polyclonal antibody

• Background :

  Reversion inducing cysteine rich protein with kazal motifs (RECK) Homo sapiens The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  RECK; ST15; Reversion-inducing cysteine-rich protein with Kazal motifs; hRECK; Suppressor of tumorigenicity 15 protein

• Swiss Prot :

  O95980

• Reactivity :

  Human, Rat, Mouse

• Immunogen :

  Synthetic peptide, corresponding to Human RECK.

• Conjugation :

  Unconjugated

• Applications :

  WB IF ICC

• Dilution :

  WB 1:500 - 1:1000 IF 1:50 - 1:200 ICC 1:50 - 1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 110 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  RECK polyclonal antibody detects endogenous levels of RECK protein.

• Applications Notes :

  Western blot (WB) analysis of RECK pAb at 1:500 dilution LaneA:MCF-7 whole cell lysate (40ug) LaneB:The Kidney tissue lysate of Mouse (40ug)

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4