RECK polyclonal antibody

CAT: 0384-BS65225-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS65225-01Size:50 µL
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Background
Reversion inducing cysteine rich protein with kazal motifs (RECK) Homo sapiens The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
RECK; ST15; Reversion-inducing cysteine-rich protein with Kazal motifs; hRECK; Suppressor of tumorigenicity 15 protein
Swiss Prot
O95980
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic peptide, corresponding to Human RECK.
Conjugation
Unconjugated
Applications
WB IF ICC
Dilution
WB 1:500 - 1:1000 IF 1:50 - 1:200 ICC 1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 110 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RECK polyclonal antibody detects endogenous levels of RECK protein.
Applications Notes
Western blot (WB) analysis of RECK pAb at 1:500 dilution LaneA:MCF-7 whole cell lysate (40ug) LaneB:The Kidney tissue lysate of Mouse (40ug)
Host or Source
Rabbit

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