ASMTL polyclonal antibody

• Background:

  Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. Can also hydrolyze CTP and the modified nucleotides pseudo-UTP, 5-methyl-UTP (m5UTP) and 5-methyl-CTP (m5CTP) . Has weak activity with dCTP, 8-oxo-GTP and N4-methyl-dCTP.May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.In addition, the presence of the putative catalytic domain of S-adenosyl-L-methionine binding in the C-terminal region argues for a methyltransferase activity (Probable) .

• Structure Composition:

  Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

• Product Name Alternative:

  N-acetylserotonin O-methyltransferase-like protein; ASMTL

• Swiss Prot:

  O95671

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant full length protein of human ASMTL

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC

• Dilution:

  WB (1/500 - 1/2000), IHC (1/50 - 1/200)

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 75 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Recognizes endogenous levels of ASMTL protein.

• Applications Notes:

  Western blot analysis of ASMTL expression in SW620 (A), NIH3T3 (B), mouse pancreas (C), mouse testis (D) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4