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CREB monoclonal antibody

CAT: 0384-MB65907-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-MB65907-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1
Swiss Prot
P16220
Reactivity
Human, Mouse
Immunogen
Recombinant protein corresponding to human CREB.
Conjugation
Unconjugated
Related Pathways
Signaling Pathways Activating p38 MAP Kinase, MAPK Erk in Growth and Differentiation Pathway, ErbB HER Signaling, T cell receptor signaling, Inhibition of Apoptosis, Dopamine Signaling in Parkinson\'s Disease Plathway
Applications
WB, IHC
Dilution
WB (1/500 - 1/1000), IHC (1/100 - 1/200)
Purity
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 43 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of CREB protein.
Applications Notes
Western blot analysis of CREB expression in A431 (A), NIH3T3 (B) whole cell lysates.
Host or Source
Mouse

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