SERCA2 polyclonal antibody

• Background:

  This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (PubMed:16402920, PubMed:12542527) .

• Structure Composition:

  Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

• Product Name Alternative:

  ATP2B; Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; SERCA2; SR Ca (2+) -ATPase 2; Calcium pump 2; Calcium-transporting ATPase sarcoplasmic reticulum type slow twitch skeletal muscle isoform; Endoplasmic reticulum class 1/2 Ca (2+) ATPase

• Swiss Prot:

  P16615

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human SERCA2. The exact sequence is proprietary.

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC

• Dilution:

  WB (1/500 - 1/1000), IHC (1/50 - 1/200)

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 132% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 114, 130 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Recognizes endogenous levels of SERCA2 protein.

• Applications Notes:

  Western blot analysis of SERCA2 expression in mouse muscle (A), rat muscle (B) whole cell lysates.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4