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VAV2 (phospho-Y142) polyclonal antibody

CAT: 0384-BS67100-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67100-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity) .
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
Guanine nucleotide exchange factor VAV2; VAV-2
Swiss Prot
P52735
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human VAV2. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500)
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Phosphorylation
Molecular Weight
~ 100 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of VAV2 (pY142) protein.
Applications Notes
Western blot analysis of VAV2 (pY142) expression in A431 TNF-treated (A), HEK293T (B) whole cell lysates.
Host or Source
Rabbit

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