Products for Research Use Only
RegisterLogin

AMPK gamma 2 polyclonal antibody

CAT: 0384-BS67068-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS67068-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
5'-AMP-activated protein kinase subunit gamma-2; AMPK gamma2; AMPK subunit gamma-2; H91620p
Swiss Prot
Q9UGJ0
Reactivity
Human, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AMPK gamma 2. The exact sequence is proprietary.
Conjugation
Unconjugated
Related Pathways
AMPK Signaling Pathway
Applications
WB, IHC, IF/ICC
Dilution
WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500)
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of AMPK gamma 2 protein.
Applications Notes
Western blot analysis of AMPK gamma 2 expression in HEK293T (A), SGC7901 (B), rat kidney (C), rat spleen (D) whole cell lysates.
Host or Source
Rabbit

Related Products

CatalogName
BS75574-01AMPKα2 polyclonal antibody
BS74297AMPKα2 polyclonal antibody
MB10538AMPK gamma 1 monoclonal antibody
MB11915AMPK gamma 1 monoclonal antibody
BS70793-01[KO Validated] AMPKα2 polyclonal antibody
BS94020AMPKα2 (Phospho-S345) polyclonal antibody
BS1009AMPKα1/2 (D168) polyclonal antibody
BS5503-01AMPKα1/2 (N180) polyclonal antibody
BS47184-01AMPK gamma 1 Recombinant Rabbit mAb
BS46239-01AMPK gamma 1 Recombinant Rabbit mAb

Alternative Products

CatalogName
MBS839080AMPK gamma antibody
MBS8521203-01AMPK gamma 2 Polyclonal Antibody
MBS8521201-01AMPK gamma 1 Polyclonal Antibody
bs-3968RAMPK gamma 3 Polyclonal Antibody
TMAB-02536-01Anti-AMPK gamma 1 Polyclonal Antibody
NBP2-57986-25ulRabbit Polyclonal AMPK gamma 1 Antibody
GTR18308065AMPK gamma 1 Rabbit Polyclonal Antibody
GTR18306916AMPK gamma 2 Rabbit Polyclonal Antibody
GTR17724096-01AMPK gamma 3 Rabbit Polyclonal Antibody
70R-50249AMPK gamma 1 antibody

Popular Products