PLA2G4C polyclonal antibody

• Background :

  Calcium-independent phospholipase, lysophospholipase and O-acyltransferase involved in phospholipid remodeling with implications in endoplasmic reticulum membrane homeostasis and lipid droplet biogenesis (PubMed:19501189, PubMed:9705332, PubMed:10085124, PubMed:10358058, PubMed:28336330) .Preferentially hydrolyzes the ester bond of the fatty acyl group attached at the sn-2 position of phospholipids with choline and ethanolamine head groups, producing lysophospholipids that are used in deacylation-reacylation cycles (PubMed:19501189, PubMed:9705332, PubMed:10085124, PubMed:10358058, PubMed:28336330) .

• CAS Number :

  9007-83-4

• Structure Composition :

  Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

• Product Name Alternative :

  Cytosolic phospholipase A2 gamma; cPLA2-gamma; Phospholipase A2 group IVC

• Swiss Prot :

  Q9UP65

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PLA2G4C. The exact sequence is proprietary.

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB (1/500 - 1/1000)

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 80 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Recognizes endogenous levels of PLA2G4C protein.

• Applications Notes :

  Western blot analysis of PLA2G4C expression in Jurkat (A), H446 (B), mouse lung (C), rat lung (D), rat spleen (E) whole cell lysates.

• Host or Source :

  Rabbit