DSPP polyclonal antibody

• Background:

  This gene encodes two principal proteins of the dentin extracellular matrix of the tooth. The preproprotein is secreted by odontoblasts and cleaved into dentin sialoprotein and dentin phosphoprotein. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1; in some individuals, dentinogenesis imperfecta occurs in combination with an autosomal dominant form of deafness. Allelic differences due to repeat polymorphisms have been found for this gene.

• Structure Composition:

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  DPP; DSP; DGI1; DMP3; DFNA39; DSPP

• Swiss Prot:

  Q9NZW4

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human DSPP.

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB: 1:500~1:2000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Molecular Weight:

  ~ 130 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  DSPP polyclonal antibody detects endogenous levels of DSPP protein.

• Applications Notes:

  Western blot analysis of various lysates using DSPP pAb at 1:1000 dilution.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4