CCRL2 polyclonal antibody

• Background :

  Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  C-C chemokine receptor-like 2; Chemokine receptor CCR11; Chemokine receptor X; Putative MCP-1 chemokine receptor; CCRL2; CCR11, CCR6, CKRX, CRAM, HCR

• Swiss Prot :

  O00421

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthetic peptide, corresponding to Human CCRL2.

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB 1:500 - 1:1000

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 40 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  CCRL2 polyclonal antibody detects endogenous levels of CCRL2 protein.

• Applications Notes :

  Western blot (WB) analysis of CCRL2 polyclonal antibody at 1:500 dilution LaneA:A375 whole cell lysate (30ug) LaneB:H1688 whole cell lysate (30ug) LaneC:The Spleen tissue lysate of Mouse (30ug) LaneD:The Spleen tissue lysate of Rat (30ug)

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4