CCRL2 polyclonal antibody

• Background:

  Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  C-C chemokine receptor-like 2; Chemokine receptor CCR11; Chemokine receptor X; Putative MCP-1 chemokine receptor; CCRL2; CCR11, CCR6, CKRX, CRAM, HCR

• Swiss Prot:

  O00421

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide, corresponding to Human CCRL2.

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB 1:500 - 1:1000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 40 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CCRL2 polyclonal antibody detects endogenous levels of CCRL2 protein.

• Applications Notes:

  Western blot (WB) analysis of CCRL2 polyclonal antibody at 1:500 dilution LaneA:A375 whole cell lysate (30ug) LaneB:H1688 whole cell lysate (30ug) LaneC:The Spleen tissue lysate of Mouse (30ug) LaneD:The Spleen tissue lysate of Rat (30ug)

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4