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DDR2 polyclonal antibody

CAT: 0384-BS70578-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS70578-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
CD_antigen: CD167b; NTRKR3; TKT; TYRO10; Discoidin domain-containing receptor 2
Swiss Prot
Q16832
Reactivity
Human, Mouse, Rat
Conjugation
Unconjugated
Applications
WB ELISA
Dilution
WB 1:500 - 1:2000 ELISA 1:5000-1:10000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 92 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
DDR2 polyclonal antibody detects endogenous levels of DDR2 protein.
Host or Source
Rabbit

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