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CEMP1 polyclonal antibody

CAT: 0384-BS66121-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS66121-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A mineralized connective tissue known as cementum covers the root surfaces of teeth and is required for maturation of periodontal tissue. CEMP1 (cementum protein 1), also designated CP23 or cementoblastoma-derived protein 1, is a 247 amino acid nuclear and cytoplasmic protein that is thought to regulate cementoblast behavior. Expressed specifically in periodontal ligament and cementum, CEMP1 may play a role in differentiation and mineralization of non-osteogenic cells. The gene encoding CEMP1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
Cementoblastoma-derived protein 1; Cementum protein 1; Cementum protein 23; CEMP1; CEMP1_HUMAN; CP-23; CP23
Swiss Prot
Q6PRD7
Reactivity
Human
Immunogen
KLH conjugated synthetic peptide derived from human CEMP1: 151-247/247
Conjugation
Unconjugated
Applications
ELISA IHC IF ICC
Dilution
ELISA: 1:5000-1:10000 IHC: 1:100-1:500 IF: 1:100-1:500 ICC: 1:100-1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 26 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CEMP1 polyclonal antibody detects endogenous levels of CEMP1 protein.
Host or Source
Rabbit

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