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CHRM2 monoclonal antibody

CAT: 0384-MB66836-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-MB66836-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate ; this then triggers calcium ion release into the cytosol.
CAS Number
9007-83-4
Structure Composition
Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
Muscarinic acetylcholine receptor M2
Swiss Prot
P08172
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human CHRM2. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC, FC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF/ICC (1/10 - 1/50), FC (1/10 - 1/50)
Purity
This antibody is purified through a protein G column.
Modification
Unmodification
Molecular Weight
~ 55 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of CHRM2 protein.
Applications Notes
Western blot analysis of CHRM2 expression in SHSY5Y (A), human brain (B), mouse brain (C) whole cell lysates.
Host or Source
Mouse

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