Products for Research Use Only
RegisterLogin

ALPP monoclonal antibody

CAT: 0384-MB66638-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-MB66638-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Mammalian alkaline phosphatases (APs) are highly conserved zinc-containing allosteric enzymes that are able to hydrolyze and transphosphorylate a wide range of compounds. There are four known human alkaline phosphatase isozymes: TNAP (tissue-nonspecific; bone/liver/kidney), ALPP (placental), ALPP2 (germ cell), and ALPI (intestinal) . Placental alkaline phosphatase (ALPP) is bound to the plasma membrane via a glycosyl-phosphatidylinositol (GPI) anchor. It is expressed primarily in the placenta and may be involved in transplacental IgG transport. ALPP has been found to be overexpressed on the surface of several different types of solid tumor cells and elevated serum concentrations of ALPP and ALPP-like enzymes has been found to be associated with ovarian, cervical, and testicular cancer.
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Product Name Alternative
PLAP; Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1
Swiss Prot
P05187
Reactivity
Human
Immunogen
Purified recombinant fragment of human ALPP expressed in E. Coli.
Conjugation
Unconjugated
Applications
WB, IHC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/100)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of ALPP protein.
Applications Notes
Western blot analysis of ALPP expression in HepG2 (A), A431 (B), MCF7 (C) whole cell lysates.
Host or Source
Mouse

Related Products

CatalogName
BS90049ALPP polyclonal antibody
BS60863-01ALPP polyclonal antibody
MB66312ALPL Rabbit monoclonal antibody
MB9534TGG2 monoclonal antibody
MB11165Legumain monoclonal antibody
MB66180CD74 monoclonal antibody
MB11512RAP1GAP monoclonal antibody
MB66068Desmin monoclonal antibody
MB10456VCAM1 monoclonal antibody
MB66771-01LgA monoclonal antibody

Alternative Products

CatalogName
BT-MCA4043-01ALPP Monoclonal Antibody
MAB-606030061Mouse Monoclonal Antibody to ALPP
MBS9019329-01ALPP Recombinant Monoclonal Antibody
GTR18087348ALPP Mouse Monoclonal Antibody
E49Y7080ALPP Rabbit Monoclonal Antibody
MBS5305134-01Mouse monoclonal ALPP antibody
ANT-10183-100ugALPP / PLAP Monoclonal Antibody

Popular Products