Hexokinase 2 monoclonal antibody

• Background:

  Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

• Product Name Alternative:

  Hexokinase-2; Hexokinase type II; HK II; Muscle form hexokinase

• Swiss Prot:

  O08528/P27881

• Reactivity:

  Mouse, Rat, Monkey

• Immunogen:

  Recombinant human Hexokinase II protein.

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB (1/500 - 1/1000)

• Purity:

  The antibody was purified by immunogen affinity chromatography.

• Modification:

  Unmodification

• Molecular Weight:

  ~ 102 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  Recognizes endogenous levels of Hexokinase 2 protein.

• Applications Notes:

  Western blot analysis of Hexokinase 2 expression in NIH3T3 (A), COS7 (B), C6 (C) whole cell lysates.

• Host or Source:

  Mouse

• CAS Number:

  9007-83-4