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MMP9 polyclonal antibody

CAT: 0384-BS67753-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67753-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The matrix metalloproteinases (MMPs) are a family of proteases that target many extracellular proteins including other proteases, growth factors, cell surface receptors, and adhesion molecules. Among the family members, MMP-2, MMP-3, MMP-7, and MMP-9 have been characterized as important factors for normal tissue remodeling during embryonic development, wound healing, tumor invasion, angiogenesis, carcinogenesis, and apoptosis. Research studies have shown that MMP activity correlates with cancer development. One mechanism of MMP regulation is transcriptional. Once synthesized, MMP exists as a latent proenzyme. Maximum MMP activity requires proteolytic cleavage to generate active MMPs by releasing the inhibitory propeptide domain from the full-length protein.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
CLG4B; Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; GELB
Swiss Prot
P14780
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein corresponding to human MMP9. The exact sequence is proprietary.
Conjugation
Unconjugated
Related Pathways
Tumor Angiogenesis, G Protein-coupled Receptors Signaling to MAPK Erk
Applications
WB, IHC, IF/ICC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/200)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 74 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of MMP9 protein.
Applications Notes
Western blot analysis of MMP9 expression in K562 (A), Raji (B), mouse brain (C), rat kidney (D) whole cell lysates.
Host or Source
Rabbit

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