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ILF2 polyclonal antibody

CAT: 0384-BS67511-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS67511-01Size:50 µL
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Background
Chromatin-interacting protein that forms a stable heterodimer with interleukin enhancer-binding factor 3/ILF3 and plays a role in several biological processes including transcription, innate immunity or cell growth.Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus. Together with ILF3, forms an RNA-binding complex that is required for mitotic progression and cytokinesis by regulating the expression of a cluster of mitotic genes. Mechanistically, competes with STAU1/STAU2-mediated mRNA decay.Also plays a role in the inhibition of various viruses including Japanese encephalitis virus or enterovirus 717 Publications (Microbial infection) Plays a positive role in HIV-1 virus production by binding to and thereby stabilizing HIV-1 RNA, together with ILF3.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
NF45; Interleukin enhancer-binding factor 2; Nuclear factor of activated T-cells 45 kDa
Swiss Prot
Q12905
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ILF2. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 43 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of ILF2 protein.
Applications Notes
Western blot analysis of ILF2 expression in Raw264.7 (A), Beas2B (B), HCT116 (C), HEK293T (D) whole cell lysates.
Host or Source
Rabbit

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