Products for Research Use Only
RegisterLogin

MGLUR2 polyclonal antibody

CAT: 0384-BS67494-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS67494-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Metabotropic glutamate receptor 2 (mGluR2) is a class C G protein-coupled receptor for the neurotransmitter glutamate in the mammalian brain. Unlike ionotropic receptors, metabotropic receptors do not form an ion channel pore themselves but are indirectly linked to ion channels . While mGluR1 and mGluR5 activate phospholipase C, mGluR2, mGluR3, mGluR4, and mGluR6 are coupled to the inhibitory G protein Gα (i/o) and inhibit adenylyl cyclase (AC) activity . Research studies have suggested that mGluR2/3 receptors may be potential targets for the treatment of Schizophrenia . Furthermore, mGluR2 interacts with the 5HT2A serotonin receptor to form a hetero-complex in the brain. This complex is a potential pharmacological target for hallucinogenic drugs .
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
GPRC1B; MGLUR2; Metabotropic glutamate receptor 2; mGluR2
Swiss Prot
Q14416
Reactivity
Human, Mouse, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human mGLUR2. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/200)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 100 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of mGLUR2 protein.
Applications Notes
Western blot analysis of mGLUR2 expression in U87MG (A), A375 (B), C6 (C) whole cell lysates.
Host or Source
Rabbit

Related Products

CatalogName
BS90851mGluR1 polyclonal antibody
BS1146-01MGluR-6 (A865) polyclonal antibody
BS2732-01MGluR-5 (K56) polyclonal antibody
BS3430-01MGluR-2/3 (N867) polyclonal antibody
BS41300-01MGluR3 Rabbit monoclonal antibody
BS40382mGluR1 Rabbit monoclonal antibody
BS9933MmGluR-5 Rabbit monoclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS75206-01AaaaaASPH polyclonal antibody
BS5662-01CHST1 polyclonal antibody

Alternative Products

CatalogName
JOT-AP05387-01mGluR2 Polyclonal Antibody
NBP2-97220-50ulRabbit Polyclonal mGluR2 Antibody
AMM06391GPolyclonal mGluR2 (extracellular) Antibody
GTR18112589-01MGLUR2 Rabbit Polyclonal Antibody
NBP1-68855Goat Polyclonal mGluR2 Antibody
NB100-1760SSRabbit Polyclonal mGluR2/3 Antibody
NBP2-97220HRabbit Polyclonal mGluR2 Antibody [HRP]
APR12288GPolyclonal GRM2 / MGLUR2 Antibody (Internal)
NBP2-97220APCRabbit Polyclonal mGluR2 Antibody [Allophycocyanin]
NBP2-97220FRabbit Polyclonal mGluR2 Antibody [FITC]

Popular Products