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GPR146 polyclonal antibody

CAT: 0384-BS67492-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67492-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR146 (G protein-coupled receptor 146), also known as PGR8, is a 333 amino acid multi-pass transmembrane protein that belongs to the G-protein coupled receptor 1 family. Characterized as an orphan receptor for which its endogenous ligand has yet to be identified, GPR146 is thought to play a role in signaling events throughout the cell.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
PGR8; Probable G-protein coupled receptor 146; G-protein coupled receptor PGR8
Swiss Prot
Q96CH1
Reactivity
Human, Rat
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GPR146. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB, IF/ICC
Dilution
WB (1/500 - 1/1000), IF/ICC (1/50 - 1/200)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 38 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of GPR146 protein.
Applications Notes
Western blot analysis of GPR146 expression in A549 (A), Hela (B), rat lung (C) whole cell lysates.
Host or Source
Rabbit

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