Products for Research Use Only
RegisterLogin

P27 Kip1 polyclonal antibody

CAT: 0384-BS67448-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS67448-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
P27 Kip1 is a member of the Cip/Kip family of cyclin-dependent kinase inhibitors. Like its relatives, p57 Kip2 and p21 Waf1/Cip1, the ability to enforce the G1 restriction point is derived from its inhibitory binding to CDK2/cyclin E and other CDK/cyclin complexes. Expression levels of p27 are upregulated in quiescent cells and in cells treated with cAMP or other negative cell cycle regulators. Downregulation of p27 can be induced by treatment with interleukin-2 or other mitogens; this involves phosphorylation of p27 and its degradation by the ubiquitin-proteasome pathway.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1
Swiss Prot
P46527
Reactivity
Human, Rat, Dog
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human p27 Kip1. The exact sequence is proprietary.
Conjugation
Unconjugated
Related Pathways
ErbB HER Signaling, Cell Cycle Control G1 S Checkpoin, MAPK Erk in Growth and Differentiation Pathway (, PI3K AKT signaling.
Applications
WB, IHC
Dilution
WB (1/500 - 1/1000), IHC (1/50 - 1/200)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 27 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of p27 Kip1 protein.
Applications Notes
Western blot analysis of p27 Kip1 expression in Hela (A), HEK293T (B), C6 (C) whole cell lysates.
Host or Source
Rabbit

Related Products

CatalogName
BS3714-01P27 Kip1 (A181) polyclonal antibody
BS1858-01P27 Kip1 (P191) polyclonal antibody
MB66990-01P27 Kip1 monoclonal antibody
BS4851-01P27 Kip1 (phospho-T198) polyclonal antibody
BS4838-01P27 Kip1 (phospho-T187) polyclonal antibody
MB11351p27 Kip 1 monoclonal antibody
MB12172-01P27 Kip 1 monoclonal antibody
BS1205-01Cytokeratin 18 (P27) polyclonal antibody
MB11350-01Phospho-p27 Kip 1 (Ser10) monoclonal antibody
BS48993p27 KIP 1 Recombinant Rabbit mAb

Alternative Products

CatalogName
MBS2565746-01p27 KIP1 Polyclonal Antibody
NBP1-32213Rabbit Polyclonal p27/Kip1 Antibody
GTR18043290-01P27 Kip1 (A181) polyclonal antibody
GTR18153589-01P27 Kip1 Rabbit Polyclonal Antibody
E43S1858P27 Kip1 (P191) polyclonal antibody
NB100-2816Goat Polyclonal p27/Kip1 Antibody
APG01082GPolyclonal CDKN1B / p27 Kip1 Antibody (Internal)
GTR18043081-01P27 Kip1 (phospho-T187) polyclonal antibody
GTR18043092-01P27 Kip1 (phospho-T198) polyclonal antibody
GTR18108852-01P27 Kip1 (Phospho-T187) Rabbit Polyclonal Antibody

Popular Products