FADD polyclonal antibody

• Background :

  Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95 or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

• Structure Composition :

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  Mort1/F; Mort1/FADD

• Swiss Prot :

  Q61160

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of mouse FADD (NP_034305.1) .

• Conjugation :

  Unconjugated

• Applications :

  WB, IF/ICC, IP

• Dilution :

  WB,1:200 - 1:2000|IF/ICC,1:50 - 1:200|IP,1:50 - 1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  28KDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Unmodification

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4