Products for Research Use Only
RegisterLogin

PSMB8 polyclonal antibody

CAT: 0384-BS78214-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS78214-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex) . Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
PSMB8; ALDD; D6S216; D6S216E; JMP; LMP7; NKJO; PSMB5i; RING10; proteasome subunit beta 8
Swiss Prot
P28062
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PSMB8 (NP_004150.1) .
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
Refer to figures
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit

Related Products

CatalogName
MB66639-01PSMB8 monoclonal antibody
PPL01886-2aPcDNA3.1 (+) -PSMB8-3*HA
PPL01886-3PLKO.1-PSMB8 shRNA (3+1)
BS7789-01PSMB2 polyclonal antibody
BS71993-01PSMB6 polyclonal antibody
BS72485-01PSMB7 polyclonal antibody
BS75391-01PSMB2 polyclonal antibody
BS91128PSMB9 polyclonal antibody
BS72407-01PSMB3 polyclonal antibody
BS7338-01PSMB5 polyclonal antibody

Alternative Products

CatalogName
ANT-13956-50ugPSMB8 Polyclonal Antibody
MBS9466218-01PSMB8 Rabbit Polyclonal Antibody
PTX20383-01Anti-PSMB8 Polyclonal Antibody

Popular Products