PCNT polyclonal antibody

CAT: 0384-BS77928-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS77928-01Size:50 µL
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Background
The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM) . The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
KEN; PCN; MOPD2; PCNT2; PCNTB; PCTN2; SCKL4
Swiss Prot
O95613
Reactivity
Human, Rat
Immunogen
Recombinant fusion protein of human PCNT (NP_006022.3) .
Conjugation
Unconjugated
Applications
WB, IF/ICC
Dilution
WB,1:1000 - 1:2000|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
251KDa/378KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit

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