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H2-Aa polyclonal antibody

CAT: 0384-BS77661-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS77661-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Enables peptide antigen binding activity. Involved in response to interferon-gamma. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and positive regulation of T cell differentiation. Located in external side of plasma membrane and lysosome. Part of MHC class II protein complex. Is expressed in central nervous system; retina; and thymus primordium. Human ortholog (s) of this gene implicated in several diseases, including autoimmune disease (multiple) ; gastrointestinal system cancer (multiple) ; glomerulonephritis (multiple) ; hematologic cancer (multiple) ; and systemic scleroderma (multiple) . Orthologous to several human genes including HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1) .
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Ia1; H2Aa; Ia-1; H-2Aa; Aalpha; IAalpha; I-Aalpha; H2-Aa
Swiss Prot
P14434
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of mouse H2-Aa (NP_034508.2) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
28KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit

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