USP6 polyclonal antibody

• Background :

  Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

• Structure Composition :

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  USP6; HRP1; TRE17; TRE2; TRESMCR; Tre-2; USP6-short

• Swiss Prot :

  P35125

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human USP6 (NP_004496.2) .

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB,1:1000 - 1:2000

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  Refer to Figures

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Unmodification

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4