Ezrin polyclonal antibody

• Background :

  The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

• Structure Composition :

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  CVIL; CVL; HEL-S-105; VIL2; EZR; Ezrin; ezrin

• Swiss Prot :

  P15311

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human Ezrinin (NP_003370.2) .

• Conjugation :

  Unconjugated

• Applications :

  WB, IF/ICC, IP

• Dilution :

  WB,1:500 - 1:2000|IF/ICC,1:50 - 1:100|IP,1:50 - 1:100

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  90kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Unmodification

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4