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Bmi1 polyclonal antibody

CAT: 0384-BS74254-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS74254-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1) . This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
BMI1; FLVI2/BMI1; PCGF4; RNF51; flvi-2/bmi-1; Bmi1
Swiss Prot
P35226
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human Bmi1 (NP_005171.4) .
Conjugation
Unconjugated
Applications
WB, IP
Dilution
WB,1:500 - 1:2000|IP,1:50 - 1:100
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
43KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit

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