Products for Research Use Only
RegisterLogin

SHIP1 polyclonal antibody

CAT: 0384-BS74242-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS74242-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5) -trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
INPP5D; SHIP; SHIP-1; SHIP1; SIP-145; hp51CN; p150Ship
Swiss Prot
Q92835
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human SHIP1 (NP_001017915.1) .
Conjugation
Unconjugated
Applications
WB, IHC, IF/ICC
Dilution
WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
140KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Unmodification
Host or Source
Rabbit

Related Products

CatalogName
BS1595-01SHIP1 (M1014) polyclonal antibody
BS74167-01Phospho-SHIP1-Y1020 polyclonal antibody
BS91238SHIP polyclonal antibody
BS94059SHIP (Phospho-Y1020) polyclonal antibody
BS40061SHIP Rabbit monoclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS75206-01AaaaaASPH polyclonal antibody
BS65563-01Mras polyclonal antibody
BS7930-01TRPM2 polyclonal antibody
BS8744-01TPH2 polyclonal antibody

Alternative Products

CatalogName
AMM07809GPolyclonal SHIP1 Antibody
bs-3567RSHIP1 Polyclonal Antibody
GTR18103362-01SHIP1 Rabbit Polyclonal Antibody
GTR18041383-01SHIP1 (M1014) polyclonal antibody
TMAB-12769-01Anti-SHIP1 Polyclonal Antibody
bs-3567R-FITCSHIP1 Polyclonal Antibody, FITC Conjugated
bs-3567R-Cy3SHIP1 Polyclonal Antibody, Cy3 Conjugated
bs-3567R-APCSHIP1 Polyclonal Antibody, APC Conjugated
GTR18297856-01Phospho-SHIP1-Y1020 polyclonal antibody
bs-3567R-Cy7SHIP1 Polyclonal Antibody, Cy7 Conjugated

Popular Products