Phospho-Parvin alpha (Ser8) monoclonal antibody

• Background:

  Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development . Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and directed cell migration.

• Structure Composition:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

• Product Name Alternative:

  MXRA2; CH-ILKBP

• Swiss Prot:

  Q9NVD7

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic phosphopeptide corresponding to residues surrounding Ser8 of human Parvin alpha

• Conjugation:

  Unconjugated

• Applications:

  WB, ICC/IF

• Dilution:

  WB: 1/500-1/1000 IF: 1/50-1/200

• Purity:

  Affinity Purified

• Modification:

  Phosphorylated

• Molecular Weight:

  Calculated MW: 42 kDa; Observed MW: 42 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of Parvin alpha in U2OS, mouse brain, rat brain, PC-12, A549 lysates using Phospho-Parvin alpha antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4