Phospho-eIF2A (Ser51) monoclonal antibody

• Background:

  EIF2A a translation initiation factor that functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40s ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex.

• Structure Composition:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

• Product Name Alternative:

  EIF2S1; EIF2A; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alpha

• Swiss Prot:

  P05198

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic phosphopeptide corresponding to residues surrounding Ser51 of human EIF2S1

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB: 1/500-1/1000

• Purity:

  Affinity Purified

• Modification:

  Phosphorylated

• Molecular Weight:

  Calculated MW: 36 kDa; Observed MW: 36 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of Phospho-eIF2A in K562, C6, 3T3, Hela lysates using Phospho-eIF2A antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4