Cullin 3 polyclonal antibody

• Background:

  Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  CUL3; KIAA0617; Cullin-3; CUL-3

• Swiss Prot:

  Q13618

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human Cullin 3

• Conjugation:

  Unconjugated

• Applications:

  WB, IP, FC

• Dilution:

  WB: 1/500-1/1000 IP: 1/20 FC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 89 kDa; Observed MW: 89 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of Cullin 3 in SH-SY5Y lysates using Cullin 3 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4