WDR5 polyclonal antibody

• Background:

  Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein

• Swiss Prot:

  P61964

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human WDR5

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P, FC

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 37 kDa; Observed MW: 37 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of WDR5 in HeLa lysates using WDR5 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4