RBX1 polyclonal antibody

• Background :

  E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair.

• CAS Number :

  9007-83-4

• Structure Composition :

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative :

  ROC1; RNF75; BA554C12.1

• Swiss Prot :

  P62877

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human ROC1

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC-P, ICC/IF, IP, FC

• Dilution :

  WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

• Purity :

  Affinity Purified

• Modification :

  Unmodified

• Molecular Weight :

  Calculated MW: 12 kDa; Observed MW: 12 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of ROC1 in MCF-7 lysates using RBX1 antibody.

• Host or Source :

  Rabbit