CD55 polyclonal antibody

• Background:

  This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  CD55; CR; DAF; Complement decay-accelerating factor; CD55

• Swiss Prot:

  P08174

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human CD55

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC-P

• Dilution:

  WB: 1/500-1/1000 IHC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 41 kDa; Observed MW: 55-80 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of CD55 in A549 lysates using CD55 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4