CD55 polyclonal antibody

• Background :

  This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

• Structure Composition :

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative :

  CD55; CR; DAF; Complement decay-accelerating factor; CD55

• Swiss Prot :

  P08174

• Reactivity :

  Human

• Immunogen :

  A synthesized peptide derived from human CD55

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC-P

• Dilution :

  WB: 1/500-1/1000 IHC: 1/50-1/100

• Purity :

  Affinity Purified

• Modification :

  Unmodified

• Molecular Weight :

  Calculated MW: 41 kDa; Observed MW: 55-80 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of CD55 in A549 lysates using CD55 antibody.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4