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Thioredoxin Reductase 1 polyclonal antibody

CAT: 0384-BZ16838-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BZ16838-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
TR; TR1; TXNR; TRXR1; GRIM-12
Swiss Prot
Q16881
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human TXNRD1
Conjugation
Unconjugated
Applications
WB, IHC-P, ICC/IF, IP, FC
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 71 kDa; Observed MW: 55 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of TXNRD1 in Jurkat lysates; NIH/3T3 lysates using Thioredoxin Reductase 1 antibody.
Host or Source
Rabbit

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