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ATG3 polyclonal antibody

CAT: 0384-BZ16800-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BZ16800-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE) . Catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Product Name Alternative
APG3; APG3L; PC3-96; APG3-LIKE
Swiss Prot
Q9NT62
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Apg3 (Atg3)
Conjugation
Unconjugated
Applications
WB, IHC-P, ICC/IF
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Purity
Affinity Purified
Modification
Unmodified
Molecular Weight
Calculated MW: 36 kDa; Observed MW: 40 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of Apg3 in Jurkat lysates using ATG3 antibody.
Host or Source
Rabbit

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