VAMP2 polyclonal antibody

• Background:

  The SNARE complex is involved in vesicular transport and membrane fusion, a process regulated by calcium. In neurons, VAMP2 is predominantly inserted in presynaptic vesicle membranes. Assembly of VAMP2 with the plasma membrane SNAREs syntaxin 1 and SNAP25 is a key event necessary for membrane fusion and neurotransmitter release.

• Structure Composition:

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative:

  Vesicle-associated membrane protein 2 (synaptobrevin 2) ; SYB2; VAMP-2

• Swiss Prot:

  P63027

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human VAMP2

• Conjugation:

  Unconjugated

• Applications:

  WB, ICC/IF, IP, FC

• Dilution:

  WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

• Purity:

  Affinity Purified

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 13 kDa; Observed MW: 16 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of VAMP2 in mouse brain lysates using VAMP2 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4