VAMP2 polyclonal antibody

• Background :

  The SNARE complex is involved in vesicular transport and membrane fusion, a process regulated by calcium. In neurons, VAMP2 is predominantly inserted in presynaptic vesicle membranes. Assembly of VAMP2 with the plasma membrane SNAREs syntaxin 1 and SNAP25 is a key event necessary for membrane fusion and neurotransmitter release.

• Structure Composition :

  Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Product Name Alternative :

  Vesicle-associated membrane protein 2 (synaptobrevin 2) ; SYB2; VAMP-2

• Swiss Prot :

  P63027

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human VAMP2

• Conjugation :

  Unconjugated

• Applications :

  WB, ICC/IF, IP, FC

• Dilution :

  WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

• Purity :

  Affinity Purified

• Modification :

  Unmodified

• Molecular Weight :

  Calculated MW: 13 kDa; Observed MW: 16 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of VAMP2 in mouse brain lysates using VAMP2 antibody.

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4